Article
Complementation of RNA binding site mutations in MS2 coat protein heterodimers.
Nucleic acids research - 15 Jun 1996
Peabody D S, Lim F
Abstract excerpt
The coat protein of bacteriophage MS2 functions as a symmetric dimer to bind an asymmetric RNA hairpin. This implies the existence of two equivalent RNA binding sites related to one another by a 2-fold symmetry axis. In this view the symmetric binding site defined by mutations conferring the repr...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Capsid
- Capsid Proteins
- Cloning, Molecular
- DNA, Viral
- Genetic Complementation Test
- Levivirus
- Molecular Sequence Data
- Multigene Family
- Mutation
- Protein Binding
- Protein Biosynthesis
- RNA
- RNA-Binding Proteins
- Sequence Deletion
- Virus Assembly