Article
Testing transposable elements as genetic drive mechanisms using Drosophila P element constructs as a model system.
Genetica - 1 Jan 1997
Carareto C M, Kim W, Wojciechowski M F, O'Grady P, Prokchorova A V, Silva J C, Kidwell M G
Abstract excerpt
The use of transposable elements (TEs) as genetic drive mechanisms was explored using Drosophila melanogaster as a model system. Alternative strategies, employing autonomous and nonautonomous P element constructs were compared for their efficiency in driving the ry+ allele into populations homozygous for a ry- allele at the genomic rosy locus. Transformed flies were introduced at 1%, 5%, and 10% starting...
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