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Article

Mutations in ccf, a novel Drosophila gene encoding a chromosomal factor, affect progression through mitosis and interact with Pc-G mutations.

The EMBO journal - 16 Feb 1998

Kodjabachian L, Delaage M, Maurel C, Miassod R, Jacq B, Rosset R

Abstract excerpt

We report herein the isolation of ccf, a new gene located in region 82E and essential for Drosophila development. This gene, expressed throughout development, encodes a novel product of 68 kDa which is found in the nucleus during interphase and labels, in a novel pattern, centrosomes and chromosome arms during mitosis. Mutations in ccf give rise to late larvae with small imaginal discs and to adults showing...

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Identifiers

PMID: 9463384
DOI: 10.1093/emboj/17.4.1063
PMCID: PMC1170455

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