Article
Polycomb group mutants exhibit mitotic defects in syncytial cell cycles of Drosophila embryos.
Developmental biology - 15 Feb 2006
O'Dor Ester, Beck Samantha A, Brock Hugh W
Abstract excerpt
The Polycomb Group (PcG) of epigenetic regulators maintains the repressed state of Hox genes during development of Drosophila, thereby maintaining the correct patterning of the anteroposterior axis. PcG-mediated inheritance of gene expression patterns must be stable to mitosis to ensure faithful transmission of repressed Hox states during cell division. Previously, two PcG mutants, polyhomeotic and Enhancer of...
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