Article
Is ACE gene polymorphism associated with lone atrial fibrillation?
Japanese heart journal - 1 Sept 1997
Yamashita T, Hayami N, Ajiki K, Oikawa N, Sezaki K, Inoue M, Omata M, Murakawa Y
Abstract excerpt
ACE (angiotensin converting enzyme) gene genotypes have been shown to be a risk factor for development of left ventricular hypertrophy and cardiomyopathy, upon the assumption that the DD genotype is linked to higher cellular ACE activity leading to myocardial fibrosis. To test an analogous hypothesis that the DD genotype favors myocardial fibrosis in the atrium and thus promotes atrial fibrillation without any...
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