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Article

Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation.

Heart rhythm - 1 Jun 2007

Darbar Dawood, Motsinger Alison A, Ritchie Marylyn D, Gainer James V, Roden Dan M

Abstract excerpt

BACKGROUND: The angiotensin-converting enzyme (ACE) deletion allele, ACE D, is associated with increased ACE activity and adverse outcomes in cardiovascular disease. Although activation of the renin-angiotensin-aldosterone system (RAAS) now appears to play a role in the pathophysiology of atrial fibrillation (AF), it remains to be determined if ACE genotype impacts response to conventional AAD therapy in patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17556195
DOI: 10.1016/j.hrthm.2007.02.006
PMCID: PMC1948880

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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