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Article

Expression of ACE mRNA in the human atrial myocardium is not dependent on left ventricular function, ACE inhibitor therapy, or the ACE I/D genotype.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 1999

Spruth E, Zurbrügg H R, Warnecke C, Erdmann J, Pregla R, Pfautsch P, Hetzer R, Fleck E, Regitz-Zagrosek V

Abstract excerpt

The activity of the cardiac renin-angiotensin system is altered in human heart failure, but the regulatory mechanisms are unknown. We analyzed whether angiotensin-converting enzyme (ACE) mRNA expression in heart failure is altered in the atrial myocardium, and whether a correlation exists between atrial ACE mRNA expression and the parameters of left ventricular function. We also investigated whether the use of...

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Share to Angiotensin-Converting Enzyme Inhibitors
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mutagenesis, Insertional

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Source

Identifiers

PMID: 10619441
DOI: 10.1007/s001099900056

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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