Article
Single nucleotide polymorphisms in inflammatory genes and the risk of early onset of lone atrial fibrillation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Nov 2010
Henningsen Kristoffer M A, Olesen Morten S, Pedersen Maria, Nielsen Lone, Haunsø Stig, Bruunsgaard Helle, Svendsen Jesper Hastrup
Abstract excerpt
BACKGROUND: Systemic low-grade inflammation is a prognostic risk factor of atrial fibrillation (AF). OBJECTIVE: We hypothesized that genetic polymorphisms, which determine the rate of inflammatory cytokines, are associated with the risk of AF, independently of comorbidity. METHODS AND RESULTS: We included 192 patients with so-called lone AF and age 40 years or below, and 188 healthy controls. All patients were...
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