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Article

Induction of expression of MHC-class-II antigen on human thyroid carcinoma by wild-type p53.

International journal of cancer - 30 Jan 1998

Zeki K, Tanaka Y, Morimoto I, Nishimura Y, Kimura A, Yamashita U, Eto S

Abstract excerpt

Mutation of the tumor-suppressor gene p53 is involved in carcinogenetics. We investigated the role of p53 in the induction of anti-tumor immune responses by establishing a thyroid carcinoma cell line (1F3) prepared by transfection of wild-type human p53 gene into a p53-deficient cell line (FRO). Our results showed for the first time the involvement of p53 in the induction of anti-tumor immune responses, as...

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Source

Identifiers

PMID: 9455799
DOI: 10.1002/(sici)1097-0215(19980130)75:3<391::aid-ijc11>3.0.co;2-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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