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Short Communication : Unique HIV Type 1 V3 Region Sequences Derived from Six Different Regions of Brain: Region-Specific Evolution within Host-Determined Quasispecies

1 Jan 1998

Abstract excerpt

HIV type 1 viral quasispecies were amplified by polymerase chain reaction (PCR) in the hypervariable V3 region of gp120 from six different regions of the brain (right and left frontal; right and left parietal; and right and left occipital) and from the peripheral blood mononuclear cells (PBMCs) of a patient who died of AIDS dementia complex (ADC). Cloning and sequencing of the entire V3 region suggested the...

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Identifiers

PMID: 9453248
DOI: 10.1089/aid.1998.14.25

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