Article
Simian immunodeficiency virus envelope compartmentalizes in brain regions independent of neuropathology.
Journal of neurovirology - 1 Apr 2006
Chen Maria F, Westmoreland Susan, Ryzhova Elena V, Martín-García Julio, Soldan Samantha S, Lackner Andrew, González-Scarano Francisco
Abstract excerpt
Simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) gp160s obtained from the brain are often genetically distinct from those isolated from other organs, suggesting the presence of brain-specific selective pressures or founder effects that result in the compartmentalization of viral quasi-species. Whereas HIV has also been found to compartmentalize within different regions of the brain, the...
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