Article
HIV dementia patients exhibit reduced viral neutralization and increased envelope sequence diversity in blood and brain.
AIDS (London, England) - 27 Sept 2002
Van Marle Guido, Rourke Sean B, Zhang Kunyan, Silva Claudia, Ethier Julie, Gill M John, Power Christopher
Abstract excerpt
OBJECTIVES: To examine the relationship between the humoral immune response and viral envelope diversity among HIV/AIDS patients with or without HIV-associated dementia (HAD). METHODS: Whole blood and sera were collected from age- and disease-progression matched AIDS-defined patients with and without neuro-cognitive impairment at two centers. Peripheral blood mononuclear cells were isolated from whole blood and...
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