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Article

Genetic dissection of meiotic cytokinesis in Drosophila males.

Molecular biology of the cell - 1 May 2004

Giansanti Maria Grazia, Farkas Rebecca M, Bonaccorsi Silvia, Lindsley Dan L, Wakimoto Barbara T, Fuller Margaret T, Gatti Maurizio

Abstract excerpt

We have used Drosophila male meiosis as a model system for genetic dissection of the cytokinesis mechanism. Drosophila mutants defective in meiotic cytokinesis can be easily identified by their multinucleate spermatids. Moreover, the large size of meiotic spindles allows characterization of mutant phenotypes with exquisite cytological resolution. We have screened a collection of 1955 homozygous mutant male...

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Identifiers

PMID: 15004238
DOI: 10.1091/mbc.e03-08-0603
PMCID: PMC404041

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