[Genes and enzymes of the xenobiotic-metabolizing system in cancer pathology].

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Article

[Genes and enzymes of the xenobiotic-metabolizing system in cancer pathology].

Voprosy meditsinskoi khimii - 1 Jan 2000

Liakhovich V V, Vavilin V A, Gutkina N I, Laktionova I P, Makarova S I, Mitrofanov D V, Ostashevskiĭ V A, Chasovnikova O B

Abstract excerpt

The paper presents the results of study on polymorfisms of xenobiotic biotransformation enzymes (CYP1A1, glutathione S-transferase MI and N-acetyltransferase 2) and p53 tumor suppressor protein in patients with lung, stomach and intestine cancer. The frequency of CYP1A1-Val allele in all studied...

Topics

Age Factors
Alleles
Arylamine N-Acetyltransferase
Biomarkers
Biotransformation
Cytochrome P-450 CYP1A1
Genotype
Glutathione Transferase
Humans
Middle Aged
Neoplasms
Phenotype
Polymorphism, Genetic
Tumor Suppressor Protein p53
Xenobiotics

Source

Open in PubMed

Identifiers

PMID: 9446323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9446323-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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