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Article

[Genes and enzymes of the xenobiotic-metabolizing system in cancer pathology].

Voprosy meditsinskoi khimii - 1 Jan 2000

Liakhovich V V, Vavilin V A, Gutkina N I, Laktionova I P, Makarova S I, Mitrofanov D V, Ostashevskiĭ V A, Chasovnikova O B

Abstract excerpt

The paper presents the results of study on polymorfisms of xenobiotic biotransformation enzymes (CYP1A1, glutathione S-transferase MI and N-acetyltransferase 2) and p53 tumor suppressor protein in patients with lung, stomach and intestine cancer. The frequency of CYP1A1-Val allele in all studied cancer groups was 3 to 5 times higher than in healthy control group. The carriers of homozygous glutathione...

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PMID: 9446323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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