Article
[Role of gene polymorphisms of phase II of xenobiotic biotransformation from glutathione-S-transferase and N-acetyltransferase families in susceptibility to lung cancer among Mayak workers].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Rusinova G G, Azizova T V, Viazovskaia N S, Glazkova I V, Gur'ianov M Iu, Osovets S V
Abstract excerpt
An association between polymorphous (allelic) gene variants of phase II of enzymatic xenobiotic biotransformation (EXB) of multigene families of glutathione-S-transferase (GSTs) GSTM1*0, GSTT1*0, GSTP1*B Ile105Val, and N-acetyltransferase (NAT) NAT2*6 590G>A, NAT2*5 481C>T, as well as lung cancer in Mayak workers exposed occupationally to prolonged external γ-rays and internal α-radiation from incorporated 239Pu...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.