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Article

[Role of ancestral genotypes of the genes of xenobiotics biotransformation in susceptibility to lung cancer among Mayak workers].

Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000

Rusinova G G, Azizova T V, Viazovskaia N S, Gur'ianov M Iu, Osovets I V, Glazkova

Abstract excerpt

An association between polymorphous (allelic) variants of genes of the 1st Phase of enzymatic xenobiotic biotransformation (EXB) in the superfamily of cytochromes P450 gene CYP1A1 * 2A (ml polymorphism), CYP1A1 * 2C (m2 polymorphism), gene CYP2E1 * 6 (C polymorphism), and between polymorphous vari- ants of gene of the 2nd EXB Phase of mircosomal epoxide hydrolase mEPOX Tyr113His (EH3 polymor- phism), and...

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PMID: 25427367

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