Article
Helicobacter pylori and the null genotype of glutathione-S-transferase-mu in patients with gastric adenocarcinoma.
Cancer - 15 Jan 1998
Ng E K, Sung J J, Ling T K, Ip S M, Lau J Y, Chan A C, Liew C T, Chung S C
Abstract excerpt
BACKGROUND: Chronic Helicobacter pylori infection now is recognized as an important causative agent for gastric carcinoma. However, only a small minority of infected individuals develop the malignancy, even in areas with a high prevalence of gastric carcinoma. It has been postulated that the absence of glutathione-S-transferase-mu (GST-mu), which impairs detoxification of exogenous carcinogens, might predispose...
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