Article
Glutathione S-transferase M1 null genotype associated with gastric cancer among Asians.
Digestive diseases and sciences - 1 Jul 2010
Wang Hong, Zhou Yong, Zhuang Wen, Yin Yi-Qiong, Liu Guan-Jian, Wu Tai-Xiang, Yao Xun, Du Liang, Wei Mao-Ling, Wu Xiao-Ting
Abstract excerpt
PURPOSE: The Glutathione S-transferases (GSTs) play multiple roles in the pathogenesis and treatment of cancer. Studies investigating the association between Glutathione S-transferase M1 (GSTM1) null genotype and gastric cancer risk report conflicting results. The purpose of this study was to quantitatively summarize the evidence for such a relationship. RESULTS: This meta-analysis included 35 studies, which...
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