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Article

Glutathione S-transferase M1 null genotype contributes to increased risk of esophageal carcinoma in Chinese population.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2013

Zhong Shan, Zhao Wei, Lu Chaojing, Li Bailing, Yuan Yang, Guo Danfeng, Chang Zhijie, Jiao Binhua, Yang Lixin

Abstract excerpt

Glutathione S-transferases (GSTs) play important roles in the detoxification of electrophilic carcinogens, and GSTM1 null genotype is associated with the dysfunction of GSTs. Previous studies investigating the association between GSTM1 null genotype and risk of esophageal carcinoma in Chinese provided inconsistent findings. To provide a more precise estimation on the association between GSTM1 null genotype and...

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PMID: 23625656
DOI: 10.1007/s13277-013-0790-3

Genes

GSTM1

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