Article
The GSTM1 null genotype increased risk of gastric cancer: a meta-analysis based on 46 studies.
PloS one - 1 Jan 2013
Zhao Yi, Deng Xin, Song Guoqing, Qin Shibo, Liu Zhanzhan
Abstract excerpt
BACKGROUND: Glutathione S-transferases M1 (GSTM1) is an important phase II metabolizing enzyme. The null genotype of GSTM1 causes total loss of GSTM1 enzyme activity and numerous studies have investigated the association between GSTM1 null genotype and gastric cancer risk. METHODS: This meta-analysis was designed to investigate the relationship between GSTM1 null genotype and susceptibility to gastric cancer and...
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