Article
GSTT1 and GSTM1 null genotypes and the risk of gastric cancer: a case-control study in a Chinese population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
Setiawan V W, Zhang Z F, Yu G P, Li Y L, Lu M L, Tsai C J, Cordova D, Wang M R, Guo C H, Yu S Z, Kurtz R C
Abstract excerpt
Glutathione S-transferase (GST) enzymes are involved in detoxification of many potentially carcinogenic compounds. The homozygous deletions or null genotypes of GSTT1 (theta class) and GSTM1 (mu class) genes may be associated with an increased risk of cancer. Few studies have evaluated the relationship between GSTT1, GSTM1 and the risk of gastric cancer, as well as the potential interactions between these genetic...
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