Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells.

doi:10.1161/01.res.82.1.7

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Article

Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells.

Circulation research - 1 Jan 2000

Ishida M, Ishida T, Thomas S M, Berk B C

Abstract excerpt

Among the angiotensin II (Ang II)-mediated signal events likely to be important in vascular smooth muscle cells (VSMCs) is activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2). The upstream mediators by which Ang II activates ERK1/2 remain poorly defined. Recently, we showed that...

Topics

Angiotensin II
Animals
Calcium-Calmodulin-Dependent Protein Kinases
Cells, Cultured
Enzyme Activation
Enzyme Inhibitors
Genetic Vectors
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mitogen-Activated Protein Kinase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitogen-Activated Protein Kinase 3

Mitogen-Activated Protein Kinases

Muscle, Smooth, Vascular

Mutation

Oncogene Protein pp60(v-src)

Protein-Tyrosine Kinases

Source

Open in PubMed

Identifiers

PMID: 9440699
DOI: 10.1161/01.res.82.1.7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9440699-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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