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Article

Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2005

Krymskaya Vera P, Goncharova Elena A, Ammit Alaina J, Lim Poay N, Goncharov Dmitry A, Eszterhas Andrew, Panettieri Reynold A

Abstract excerpt

Airway smooth muscle (ASM) hypertrophy and hyperplasia, important pathological features in chronic severe asthma, likely contribute to irreversible airflow obstruction. Despite considerable research effort, the precise cellular mechanisms that modulate ASM growth remain unknown. Src, a nonreceptor tyrosine kinase proto-oncogene, reportedly modulates cell proliferative responses to growth factors, contractile...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15746183
DOI: 10.1096/fj.04-2869fje

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration.PMID 15746183Read ↗

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