Article
Bcl I polymorphism in the fibrinogen beta-chain gene is associated with the risk of familial myocardial infarction by increasing plasma fibrinogen levels. A case-control study in a sample of GISSI-2 patients.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 1997
Zito F, Di Castelnuovo A, Amore C, D'Orazio A, Donati M B, Iacoviello L
Abstract excerpt
The aim of this study was to investigate the association of the Bcl I beta-chain fibrinogen polymorphism with the risk of acute myocardial infarction (AMI) and its relationship with fibrinogen levels in the Italian population. We studied 102 AMI patients, selected within the framework of the GISSI-2 trial, who had a familial history of arterial thrombosis (at least one first-degree relative suffering from AMI or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.