Article
Structural requirements for enzymatic formation of threonylcarbamoyladenosine (t6A) in tRNA: an in vivo study with Xenopus laevis oocytes.
RNA (New York, N.Y.) - 1 Jan 1998
Morin A, Auxilien S, Senger B, Tewari R, Grosjean H
Abstract excerpt
We have investigated the specificity of the eukaryotic enzymatic machinery that transforms adenosine at position 37 (3' adjacent to anticodon) of several tRNAs into threonylcarbamoyladenosine (t6A37). To this end, 28 variants of yeast initiator tRNAMet and yeast tRNAVal, devoid of modified nucleo...
Topics
- Adenosine
- Animals
- Base Composition
- Base Sequence
- Cytoplasm
- Databases, Factual
- Female
- Microinjections
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Oocytes
- RNA, Fungal
- RNA, Transfer
- RNA, Transfer, Met
- Uridine
- Xenopus laevis