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Article

Exploiting pleiotropy to map genes for oligogenic phenotypes using extended pedigree data.

Genetic epidemiology - 1 Jan 1997

Comuzzie A G, Mahaney M C, Almasy L, Dyer T D, Blangero J

Abstract excerpt

We investigated the utility of two approaches for exploiting pleiotropy to search for genes influencing related traits. To do this we first assessed the genetic correlations among a set of five closely related quantitative traits (Q1, Q2, Q3, Q4, Q5). We then used the genetic correlations among these five traits both to remove the common genetic effects of the four remaining traits, thereby identifying the unique...

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Identifiers

PMID: 9433610
DOI: 10.1002/(SICI)1098-2272(1997)14:6<975::AID-GEPI69>3.0.CO;2-I

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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