Article
Using multivariate genetic modeling to detect pleiotropic quantitative trait loci.
Behavior genetics - 1 Mar 1996
Boomsma D I
Abstract excerpt
Large numbers of sibling pairs or other relatives are needed to detect linkage between a quantitative trait locus (QTL) and a marker, especially if the variance of the QTL is low relative to the total phenotypic variance of the trait. One strategy to increase the power to detect linkage is to reduce the environmental variance in the trait under analysis. This approach was explored by carrying out a series of...
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