Article
Modeling the phenotype in parametric linkage analysis of bipolar disorder.
Genetic epidemiology - 1 Jan 1997
Turecki G, Rouleau G, Morgan K
Abstract excerpt
The definition of phenotype is a major problem in genetic studies of psychiatric disorders. Most linkage studies in bipolar disorder have defined the phenotype as a dichotomous trait and have usually employed different hierarchical classifications in order to overcome uncertainty resulting from p...
Topics
- Bipolar Disorder
- Genetic Linkage
- Humans
- Lod Score
- Models, Genetic
- Models, Statistical
- Penetrance
- Phenotype
- Risk Factors