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Article

Interdonor variability of platelet response to thrombin receptor activation: influence of PlA2 polymorphism.

British journal of haematology - 1 Dec 1997

Lasne D, Krenn M, Pingault V, Arnaud E, Fiessinger J N, Aiach M, Rendu F

Abstract excerpt

Considering that platelet response to thrombin receptor activation might be critical for the development of arterial thrombosis, we measured the dense granule release under stimulation by the thrombin receptor activating peptide (TRAP) in a series of 102 healthy volunteers. The threshold TRAP concentration which initiated a secretion ranged from 3 to 20 microM. A good concordance (79%, k=0.677) between two tests...

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Source

Identifiers

PMID: 9432025
DOI: 10.1046/j.1365-2141.1997.4973300.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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