Article
Thrombin generation abnormalities in commonly encountered platelet function disorders.
International journal of laboratory hematology - 1 Dec 2021
Sharma Tanmya, Brunet Justin G, Tasneem Subia, Smith Stephanie A, Morrissey James H, Hayward Catherine P M
Abstract excerpt
INTRODUCTION: Studies of thrombin generation (TG) with platelet-rich plasma (PRP) and platelet-poor plasma (PPP) have provided insights on bleeding disorders. We studied TG for a cohort with commonly encountered platelet function disorders (PFD). METHODS: Participants included 40 controls and 31 with PFD due to: nonsyndromic dense granule (DG) deficiency (PFD-DGD, n = 9), RUNX1 haploinsufficiency (n = 6) and...
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