Article
Decreased susceptibility to fluoroquinolones and gyrA gene mutation in the Salmonella enterica serovar Typhi and Paratyphi A isolated in Katmandu, Nepal, in 2003.
Diagnostic microbiology and infectious disease - 1 Apr 2006
Shirakawa Toshiro, Acharya Bishnu, Kinoshita Shohiro, Kumagai Shunichi, Gotoh Akinobu, Kawabata Masato
Abstract excerpt
Typhoid fever is the most common clinical diagnosis among febrile patients presenting to hospital in Katmandu. Salmonella enterica serovar Typhi (S. enterica serovar Typhi) and Salmonella enterica serovar Paratyphi A (S. enterica serovar Paratyphi A) with decreased susceptibility to fluoroquinolones and resistance to nalidixic acid are common in recent years. In the present study, we examined the in vitro...
Topics
- Anti-Bacterial Agents
- DNA Gyrase
- Drug Resistance, Multiple, Bacterial
- Fluoroquinolones
- Genes, Bacterial
- Humans
- Mutation
- Nepal
- Salmonella paratyphi A
- Salmonella typhi
- Typhoid Fever