Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones.

doi:10.1128/AAC.00963-10

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Article

Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones.

Antimicrobial agents and chemotherapy - 1 Dec 2010

Parry Christopher M, Thuy Chau Tran, Dongol Sabina, Karkey Abhilasha, Vinh Ha, Chinh Nguyen Tran, Duy Pham Thanh, Thieu Nga Tran Vu, Campbell James I, Van Minh Hoang Nguyen, Arjyal Amit, Bhutta Zulfiqar A, Bhattacharya Sujit K, Agtini Magdarina D, Dong Baiqing, Canh Do Gia, Naheed Aliya, Wain John, Tinh Hien Tran, Basnyat Buddha, Ochiai Leon, Clemens John, Farrar Jeremy J, Dolecek Christiane, Baker Stephen

Abstract excerpt

Infections with Salmonella enterica serovar Typhi isolates that have reduced susceptibility to ofloxacin (MIC ≥ 0.25 μg/ml) or ciprofloxacin (MIC ≥ 0.125 μg/ml) have been associated with a delayed response or clinical failure following treatment with these antimicrobials. These isolates are not detected as resistant using current disk susceptibility breakpoints. We examined 816 isolates of S. Typhi from seven...

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Identifiers

PMID: 20837759
DOI: 10.1128/AAC.00963-10
PMCID: PMC2981260

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