Article
<i>Helicobacter pylori</i> Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging
16 Jan 1998
Abstract excerpt
The bacterium Helicobacter pylori is the causative agent for peptic ulcer disease. Bacterial adherence to the human gastric epithelial lining is mediated by the fucosylated Lewis b (Leb) histo-blood group antigen. The Leb-binding adhesin, BabA, was purified by receptor activity-directed affinity tagging. The bacterial Leb-binding phenotype was associated with the presence of the cag pathogenicity island among...
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