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<i>Helicobacter pylori</i> colonization of the human gastric epithelium: A bug's first step is a novel target for us

22 Dec 2009

Abstract excerpt

After Helicobacter pylori enters the stomach, three steps are vital for infection: (i) establishing colonization; (ii) evading host immunity; and (iii) invading gastric mucosa; the last step is what is associated with diverse outcomes. Urease activity and motility mediated by the flagella of H. pylori are important in harboring colonies beneath the gastric mucus in niches adjacent to the epithelium. Several...

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PMID: 20136973
DOI: 10.1111/j.1440-1746.2009.06141.x

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