Article
The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators.
FEBS letters - 1 Dec 1997
Wolfger H, Mahé Y, Parle-McDermott A, Delahodde A, Kuchler K
Abstract excerpt
The yeast transcription factors Pdr1 and Pdr3 control pleiotropic drug resistance (PDR) development, since they regulate expression of ATP-binding cassette (ABC) drug efflux pumps through binding to cis-acting sites known as PDREs (PDR responsive elements). In this report, we show by Northern blotting, gel shift mobility assays and DNase I footprinting that transcription of the ABC genes PDR10 and PDR15 is also...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.