Article
The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo.
The Journal of biological chemistry - 11 Oct 1996
Mahé Y, Lemoine Y, Kuchler K
Abstract excerpt
Multiple or pleiotropic drug resistance in the yeast Saccharomyces cerevisiae can arise from overexpression of the Pdr5 and Snq2 ATP binding cassette multidrug transporters. Expression of Pdr5 and Snq2 is regulated by the two transcription factors Pdr1 and Pdr3, as multidrug-resistant pdr1 and pd...
Topics
- ATP-Binding Cassette Transporters
- Biological Transport
- Cell Membrane
- DNA-Binding Proteins
- Estradiol
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genotype
- Humans
- Membrane Proteins
- Receptors, Estrogen
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Trans-Activators
- Transcription Factors