Article
The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs.
Development (Cambridge, England) - 1 Dec 1997
Sotillos S, Roch F, Campuzano S
Abstract excerpt
The Notch transmembrane protein is the receptor of an evolutionary conserved pathway that mediates intercellular signalling leading to the specification of different cell types during development. In this pathway, many aspects of the signal transduction mechanism remain poorly understood, especia...
Topics
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Body Patterning
- Calcium-Binding Proteins
- DNA Transposable Elements
- DNA-Binding Proteins
- Disintegrins
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Insect Proteins
- Intercellular Signaling Peptides and Proteins
- Jagged-1 Protein
- Larva
- Membrane Proteins
- Metalloendopeptidases
- Mutation