Article
Dopamine D1-deficient mutant mice do not express the late phase of hippocampal long-term potentiation.
Neuroreport - 10 Nov 1997
Matthies H, Becker A, Schröeder H, Kraus J, Höllt V, Krug M
Abstract excerpt
The possible involvement of the dopamine D1 receptor subtype in mechanisms of long-term potentiation (LTP) of the Schaffer collateral-commissural input of CA1 neurones was investigated using D1-deficient mutant mice. In transversal hippocampus slices from mice lacking the D1 receptor a normal post-tetanic and short-term potentiation could be induced after applying a triple 100 Hz tetanization. However, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.