Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defects in assembly of the extracellular matrix are responsible for altered morphogenesis of a Candida albicans phr1 mutant.

Journal of bacteriology - 1 Jan 1998

Popolo L, Vai M

Abstract excerpt

Analysis of Candida albicans cells using antibodies directed against Gas1p/Ggp1p, Saccharomyces cerevisiae homolog of Phr1p, revealed that Phr1p is a glycoprotein of about 88 kDa whose accumulation increases with the rise of external pH. This polypeptide is present both in the yeast form and during germ tube induction. In the Phr1- cells at pH 8 the solubility of glucans in alkali is greatly affected. In the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Enzyme Inhibitors
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen-Ion Concentration

Share to Membrane Glycoproteins

Share to Molecular Weight

Share to Morphogenesis

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 9422607
DOI: 10.1128/JB.180.1.163-166.1998
PMCID: PMC106863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defects in assembly of the extracellular matrix are responsible for altered morphogenesis of a Candida albicans phr1 mutant.PMID 9422607Read ↗

PHR1, a pH-regulated gene of Candida albicans encoding a glucan-remodelling enzyme, is required for adhesion and invasion.Semantic proximity Read ↗

Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling.Semantic proximity Read ↗

PHR1, a pH-regulated gene of Candida albicans, is required for morphogenesis.Semantic proximity Read ↗

The Candida albicans pH-regulated KER1 gene encodes a lysine/glutamic-acid-rich plasma-membrane protein that is involved in cell aggregation.Semantic proximity Read ↗

The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants.Semantic proximity Read ↗

The Candida albicans HYR1 gene, which is activated in response to hyphal development, belongs to a gene family encoding yeast cell wall proteinsSemantic proximity Read ↗

PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes.Semantic proximity Read ↗

RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.Semantic proximity Read ↗

PHR2 of Candida albicans encodes a functional homolog of the pH-regulated gene PHR1 with an inverted pattern of pH-dependent expression.Semantic proximity Read ↗

The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties.Semantic proximity Read ↗

Transcriptional expression of PHR2 is positively controlled by the calcium signaling transcription factor Crz1 through its binding motif in the promoterSemantic proximity Read ↗

pH Regulates White-Opaque Switching and Sexual Mating in Candida albicansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.