Article
The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants.
Molecular microbiology - 1 Feb 2000
Kapteyn J C, Hoyer L L, Hecht J E, Müller W H, Andel A, Verkleij A J, Makarow M, Van Den Ende H, Klis F M
Abstract excerpt
In Candida albicans wild-type cells, the beta1, 6-glucanase-extractable glycosylphosphatidylinositol (GPI)-dependent cell wall proteins (CWPs) account for about 88% of all covalently linked CWPs. Approximately 90% of these GPI-CWPs, including Als1p and Als3p, are attached via beta1,6-glucan to beta1,3-glucan. The remaining GPI-CWPs are linked through beta1,6-glucan to chitin. The beta1,6-glucanase-resistant...
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