Article
PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes.
Fungal genetics and biology : FG & B - 1 May 2007
Eckert Sabine E, Heinz Werner J, Zakikhany Katherina, Thewes Sascha, Haynes Ken, Hube Bernhard, Mühlschlegel Fritz A
Abstract excerpt
Transglucosidases play a significant role in fungal cell wall biosynthesis. We identified three as yet undescribed genes encoding beta-glucan transglucosidases, homologues of the pH-regulated PHR1 and PHR2, in the genome of the pathogenic yeast Candida albicans. Transcript levels of the gene PGA4 encoding a putative GPI-anchored protein were elevated in C. albicans wild-type cells during infection of...
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