Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contributions of N-linked glycosylation to the expression of a functional alpha7-nicotinic receptor in Xenopus oocytes.

Journal of neurochemistry - 1 Jan 1998

Chen D, Dang H, Patrick J W

Abstract excerpt

The alpha7 subunit of the neuronal nicotinic acetylcholine receptor, when expressed in Xenopus oocytes, forms homooligomeric ligand-gated ion channels that are blocked by a snake toxin, alpha-bungarotoxin. The amino-terminal extracellular domain of the alpha7 sequence has three consensus sites for asparagine-linked glycosylation (N46DS, N90MS, and N133AS). In this study, we show that alpha7 expressed either in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Membrane
Share to Glycosylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Transfection

Source

Identifiers

PMID: 9422381
DOI: 10.1046/j.1471-4159.1998.70010349.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contributions of N-linked glycosylation to the expression of a functional alpha7-nicotinic receptor in Xenopus oocytes.PMID 9422381Read ↗

N-linked glycans are required on epithelial Na+ channel subunits for maturation and surface expression.Semantic proximity Read ↗

N-glycosylation sites on the nicotinic ACh receptor subunits regulate receptor channel desensitization and conductance.Semantic proximity Read ↗

Lectin-induced inhibition of desensitization of the kainate receptor GluR6 depends on the activation state and can be mediated by a single native or ectopic N-linked carbohydrate side chain.Semantic proximity Read ↗

Molecular determinants conferring alpha-toxin resistance in recombinant DNA-derived acetylcholine receptors.Semantic proximity Read ↗

Role of the N-terminal alpha-helix in biogenesis of alpha7 nicotinic receptors.Semantic proximity Read ↗

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution.Semantic proximity Read ↗

Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function.Semantic proximity Read ↗

Glycosylation of shaker potassium channel protein in insect cell culture and in Xenopus oocytes.Semantic proximity Read ↗

Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X7 reveals a key residue important for receptor function.Semantic proximity Read ↗

Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses.Semantic proximity Read ↗

Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT₇a receptor.Semantic proximity Read ↗

Characterization of Na,K-ATPase and H,K-ATPase enzymes with glycosylation-deficient beta-subunit variants by voltage-clamp fluorometry in Xenopus oocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.