Contributions of N-linked glycosylation to the expression of a functional alpha7-nicotinic receptor in Xenopus oocytes.

doi:10.1046/j.1471-4159.1998.70010349.x

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Article

Contributions of N-linked glycosylation to the expression of a functional alpha7-nicotinic receptor in Xenopus oocytes.

Journal of neurochemistry - 1 Jan 1998

Chen D, Dang H, Patrick J W

Abstract excerpt

The alpha7 subunit of the neuronal nicotinic acetylcholine receptor, when expressed in Xenopus oocytes, forms homooligomeric ligand-gated ion channels that are blocked by a snake toxin, alpha-bungarotoxin. The amino-terminal extracellular domain of the alpha7 sequence has three consensus sites fo...

Topics

Amino Acid Sequence
Animals
COS Cells
Carbohydrate Sequence
Cell Membrane
Female
Glycosylation
Male
Membrane Proteins
Molecular Sequence Data
Mutation
Oocytes
Rats
Receptors, Nicotinic
Transfection
Xenopus

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