Article
Activity and phenotype of natural killer cells in peptide transporter (TAP)-deficient patients (type I bare lymphocyte syndrome).
The Journal of experimental medicine - 5 Jan 1998
Zimmer J, Donato L, Hanau D, Cazenave J P, Tongio M M, Moretta A, de la Salle H
Abstract excerpt
In this paper we describe the function and phenotype of natural killer (NK) lymphocytes from HLA class I-deficient patients. These cells are, as has been previously reported, unable to lyse HLA class I- K562 cells, but are able to perform antibody-dependent cellular cytotoxicity (ADCC), although with lower efficiency as compared to NK cells from normal individuals. Transporter associated to antigen processing...
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