Article
Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes.
Blood - 1 Sept 2003
Zambello Renato, Falco Michela, Della Chiesa Mariella, Trentin Livio, Carollo Davide, Castriconi Roberta, Cannas Giovanna, Carlomagno Simona, Cabrelle Anna, Lamy Thierry, Agostini Carlo, Moretta Alessandro, Semenzato Gianpietro, Vitale Massimo
Abstract excerpt
Using monoclonal antibodies (mAbs) specific for different natural killer (NK) receptors, we studied the lymphocyte population from 18 patients with NK-type lymphoproliferative disease of granular lymphocytes (LDGL). The analysis of both resting and cultured NK cell populations demonstrated that these patients are frequently characterized by NK cells displaying a homogeneous staining with given anti-killer Ig-like...
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