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Article

Intracellular transport of the DM-20 bearing shaking pup (shp) mutation and its possible phenotypic consequences.

Journal of neuroscience research - 1 Dec 1997

Tosic M, Matthey B, Gow A, Lazzarini R A, Matthieu J M

Abstract excerpt

Paralytic tremor (pt) in rabbits and shaking pup (shp) in dogs are allelic dysmyelinated mutants of the proteolipid protein (Plp) gene. Both mutations affect the same amino acid, histidine36, which is replaced by glutamine in pt and by proline in shp. Phenotypic expression of these two mutations is very different. Paralytic tremor presents a much milder form of dysmyelination than shaking pup. The number of...

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Identifiers

PMID: 9418971
DOI: 10.1002/(SICI)1097-4547(19971201)50:5<844::AID-JNR20>3.0.CO;2-#

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Intracellular transport of the DM-20 bearing shaking pup (shp) mutation and its possible phenotypic consequences.PMID 9418971Read ↗

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