Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paralytic tremor (pt): a new allele of the proteolipid protein gene in rabbits.

Journal of neurochemistry - 1 Dec 1994

Tosic M, Dolivo M, Domańska-Janik K, Matthieu J M

Abstract excerpt

Paralytic tremor (pt) is a sex-linked mutation in rabbit that affects myelination of the CNS. Myelin in the pt brains represents approximately 30% of the normal levels. Previously we showed that the pt mutation affects primarily proteolipid protein (Plp) gene expression. In the present study we i...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
DNA, Complementary
Genetic Linkage
Humans
Molecular Sequence Data
Mutation
Myelin Proteins
Myelin Proteolipid Protein
Myelin Sheath

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

RNA, Messenger

Rabbits

Sequence Homology

Sex Chromosomes

Source

Identifiers

PMID: 7525875
DOI: 10.1046/j.1471-4159.1994.63062210.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7525875-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paralytic tremor (pt): a new allele of the proteolipid protein gene in rabbits.PMID 7525875Read ↗

Paralytic tremor (pt) rabbit: a sex-linked mutation affecting proteolipid protein-gene expression.Semantic proximity Read ↗

Myelin proteolipid protein mutation in the rabbit: a new model of Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

Rabbit paralytic tremor phenotype--a plp1 gene mutation as a model of human Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

Proteolipid/DM-20 proteins bearing the paralytic tremor mutation in peripheral nerves and transfected Cos-7 cells.Semantic proximity Read ↗

pt point mutation in plp gene results in hyperexpression of MOG in hypomyelinated rabbit.Semantic proximity Read ↗

Phenotypic diversity resulting from a point mutation.Semantic proximity Read ↗

Developmental expression of major myelin proteins in hypomyelinated pt mutant rabbit.Semantic proximity Read ↗

Expression of myelin-specific proteins during development of normal and hypomyelinated Paralytic tremor mutant rabbits. I. Studies on the brain homogenates.Semantic proximity Read ↗

Hypomyelinated pt mutant rabbit as a new model of Pelizeaus-Merzbacher disease.Semantic proximity Read ↗

Intracellular transport of the DM-20 bearing shaking pup (shp) mutation and its possible phenotypic consequences.Semantic proximity Read ↗

Expression of myelin-specific proteins during development of normal and hypomyelinated Paralytic tremor mutant rabbits. II. Studies on the purified myelin.Semantic proximity Read ↗

Jimpy-4J mouse has a missense mutation in exon 2 of the Plp gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.