Article
Paralytic tremor (pt): a new allele of the proteolipid protein gene in rabbits.
Journal of neurochemistry - 1 Dec 1994
Tosic M, Dolivo M, Domańska-Janik K, Matthieu J M
Abstract excerpt
Paralytic tremor (pt) is a sex-linked mutation in rabbit that affects myelination of the CNS. Myelin in the pt brains represents approximately 30% of the normal levels. Previously we showed that the pt mutation affects primarily proteolipid protein (Plp) gene expression. In the present study we investigated the relative effect of the pt mutation on two distinctive Plp gene products, PLP- and DM-20-specific...
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