Article
Conservation of topology, but not conformation, of the proteolipid proteins of the myelin sheath.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 1997
Gow A, Gragerov A, Gard A, Colman D R, Lazzarini R A
Abstract excerpt
The proteolipid protein gene products DM-20 and PLP are adhesive intrinsic membrane proteins that make up >/=50% of the protein in myelin and serve to stabilize compact myelin sheaths at the extracellular surfaces of apposed membrane lamellae. To identify which domains of DM-20 and PLP are positi...
Topics
- Antibodies, Monoclonal
- Apoproteins
- Cytoplasm
- DNA Transposable Elements
- Fluorescent Antibody Technique
- Humans
- Microsomes
- Mutation
- Myelin Proteolipid Protein
- Myelin Sheath
- Peptide Fragments