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Article

Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method.

Genomics - 1 Dec 1997

Reddy P H, Stockburger E, Gillevet P, Tagle D A

Abstract excerpt

The expansion of a (CAG)n trinucleotide repeat has been associated with at least eight neurological disorders in which the repeats code for polyglutamine in the protein. To identify additional genes that possess (CAG)n repeats, single-stranded cDNA clones derived from adult human brain were screened using biotinylated oligonucleotide (CAG)8, and the hybridizing complexes were isolated with strepavidin-coated...

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Identifiers

PMID: 9417904
DOI: 10.1006/geno.1997.5044

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