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Article

Detection of triplet repeat expansion in the human genome by use of hybridization signal intensity.

Analytical biochemistry - 1 Nov 2000

Sawada K, Doyu M, Tanaka F, Sobue G, Kato K

Abstract excerpt

Triplet repeat disease is a group of hereditary neurodegenerative disorders caused by expansion of trinucleotide repeats such as CAG/CTG, CGG/CCG, and GAA/TTC. Direct detection of the expansion in the patient's genome shortcuts the tedious process needed for identification of disease genes by conventional approaches. Here we describe a method to detect triplet repeat expansion from the hybridization signal...

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Source

Identifiers

PMID: 11038274
DOI: 10.1006/abio.2000.4786

Genes

GAA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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