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Article

Nuclear morphometric analysis (NMA): screening of senescence, apoptosis and nuclear irregularities.

PloS one - 1 Jan 2012

Filippi-Chiela Eduardo C, Oliveira Manuel M, Jurkovski Bruno, Callegari-Jacques Sidia Maria, da Silva Vinicius Duval, Lenz Guido

Abstract excerpt

Several cellular mechanisms affect nuclear morphology which can therefore be used to assess certain processes. Here, we present an analytic tool to quantify the number of cells in a population that present characteristics of senescence, apoptosis or nuclear irregularities through nuclear morphometric analysis. The tool presented here is based on nuclear image analysis and evaluation of size and regularity of...

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Identifiers

PMID: 22905142
DOI: 10.1371/journal.pone.0042522
PMCID: PMC3414464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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